ARHGAP45

Across TCGA patient cohorts, ARHGAP45 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,483 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARHGAP45-associated proteins across cancer lineages are EVL, FNBP1, and HCLS1. Each is linked with ARHGAP45 in more than 9 cancer types. Because this analysis shows association rather than direction, both ARHGAP45-to-partner and partner-to-ARHGAP45 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP45 versus EVL in LSCC, with a Pearson correlation of 0.75.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP45→partner) and Y-score (partner→ARHGAP45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	EVL →	+0.618	+0.770	<.001	<.001	3	10
LSCC	FNBP1 →	+0.449	+0.753	<.001	<.001	3	10
GBM	HCLS1 →	+0.832	+1.018	<.001	<.001	3	10
CCRCC	ITGAL →	+0.601	+0.520	<.001	<.001	3	10
GBM	LCP1 →	+0.932	+0.921	<.001	<.001	3	10
OV	LPXN →	+0.877	+1.000	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,483 associations by consensus.

ARHGAP45 vs EVL — LSCC

Explore this scatter interactively →