ARHGAP45

Across TCGA patient cohorts, ARHGAP45 protein abundance is significantly associated with the RNA expression of many other genes, with 20,890 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARHGAP45-associated genes across cancer lineages are CYTH4, APOBEC3H, and GRAP2. Each is linked with ARHGAP45 in more than 9 cancer types. Because this analysis shows association rather than direction, both ARHGAP45-to-partner and partner-to-ARHGAP45 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP45 versus CYTH4 in HNSC, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP45→partner) and Y-score (partner→ARHGAP45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CYTH4 →	+1.143	+0.438	<.001	<.001	3	10
BRCA	APOBEC3H →	+0.796	+0.398	<.001	<.001	3	10
HNSC	GRAP2 →	+0.896	+0.394	<.001	<.001	3	10
GBM	NCF4 →	+1.194	+0.750	<.001	<.001	3	10
OV	CSF2RB →	+1.159	+0.518	<.001	<.001	3	10
BRCA	IL2RB →	+1.298	+0.467	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,890 associations by consensus.

ARHGAP45 vs CYTH4 — HNSC

Explore this scatter interactively →