ARHGAP44

Across TCGA patient cohorts, ARHGAP44 mutation is significantly associated with the RNA expression of many other genes, with 2,158 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARHGAP44-associated genes across cancer lineages are RN7SL423P, ERP27, and MMS22L. Each is linked with ARHGAP44 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARHGAP44-to-partner and partner-to-ARHGAP44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL423P grouped by ARHGAP44-low versus ARHGAP44-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP44→partner) and Y-score (partner→ARHGAP44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RN7SL423P →	+0.165	+5.455	<.001	.001	3	3
SKCM	ERP27 →	-0.626	-1.656	.002	.001	3	3
SKCM	MMS22L →	+0.295	+1.951	.003	<.001	3	3
UCEC	LINC01943 →	+0.529	+2.202	<.001	<.001	3	2
COAD	MICU1 →	+0.568	+3.348	<.001	.005	3	2
COAD	SEC24A →	+0.662	+3.375	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,158 associations by consensus.

RN7SL423P by ARHGAP44 expression — BLCA

Explore this box plot interactively →