ARHGAP42

Across TCGA cell cohorts, ARHGAP42 mutation is significantly associated with the RNA expression of many other genes, with 422 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARHGAP42-associated genes across cancer lineages are CCDC195, GCAT, and SAMM50. Each is linked with ARHGAP42 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGAP42-to-partner and partner-to-ARHGAP42 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC195 grouped by ARHGAP42-low versus ARHGAP42-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP42→partner) and Y-score (partner→ARHGAP42) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	CCDC195 →	+0.076	+4.273	.008	.006	3	1
LARGE_INTESTINE	GCAT →	+1.482	+3.212	<.001	.006	3	1
LARGE_INTESTINE	SAMM50 →	+0.523	+3.064	.005	.009	3	1
LARGE_INTESTINE	HFE →	+0.894	+3.212	.003	.006	3	1
LARGE_INTESTINE	BAG1 →	+0.631	+3.212	.005	.006	3	1
LARGE_INTESTINE	BMPR1A →	+0.736	+3.299	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 422 associations by consensus.

CCDC195 by ARHGAP42 expression — SKIN

Explore this box plot interactively →