ARHGAP42-AS1

Across TCGA pan-cancer cohorts, ARHGAP42-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of ARHGAP42-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ARHGAP42-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ARHGAP42-AS1 is over-expressed in tumor, although a few such as THCA and COAD show the opposite, repressed pattern.

KIRC, KICH, and KIRP are the cancer types where ARHGAP42-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ARHGAP42-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.425	<.001	11	view →
KICH	Male	All	+0.676	<.001	7	view →
KIRP	All	All	+0.299	<.001	7	view →
LUAD	All	All	+0.251	<.001	7	view →
LIHC	All	All	+0.083	<.001	7	view →
THCA	Male	All	−0.307	<.001	4	view →
STAD	All	II,III,IV	+0.285	.031	2	view →
PRAD	All	All	+0.142	.036	2	view →
LUSC	All	All	+0.122	.040	2	view →
CHOL	All	All	+0.395	.038	1	view →
COAD	Female	IV	−0.160	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

ARHGAP42-AS1–KIRC

Open the KIRC breakdown →