ARHGAP4

Across TCGA cell cohorts, ARHGAP4 mutation is significantly associated with the RNA expression of many other genes, with 121 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARHGAP4-associated genes across cancer lineages are OR14K1, OR6F1, and CCL19. Each is linked with ARHGAP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGAP4-to-partner and partner-to-ARHGAP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR14K1 grouped by ARHGAP4-low versus ARHGAP4-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP4→partner) and Y-score (partner→ARHGAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR14K1 →	+0.156	+3.906	<.001	.002	3	1
OVARY	OR6F1 →	+0.266	+3.841	<.001	.003	3	1
OVARY	CCL19 →	+0.071	+3.444	<.001	.003	3	1
OVARY	OR52N2 →	+0.087	+3.974	<.001	.002	3	1
OVARY	TREML4 →	+0.134	+3.643	<.001	.002	3	1
OVARY	OR1J2 →	+0.047	+4.260	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 121 associations by consensus.

OR14K1 by ARHGAP4 expression — OVARY

Explore this box plot interactively →