ARHGAP36

Across TCGA patient cohorts, ARHGAP36 mutation is significantly associated with the RNA expression of many other genes, with 4,573 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARHGAP36-associated genes across cancer lineages are MIR6803, SPATA41, and GABRE. Each is linked with ARHGAP36 in more than 3 cancer types. Because this analysis shows association rather than direction, both ARHGAP36-to-partner and partner-to-ARHGAP36 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6803 grouped by ARHGAP36-low versus ARHGAP36-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP36→partner) and Y-score (partner→ARHGAP36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR6803 →	+0.173	+3.306	<.001	.003	3	3
LUAD	SPATA41 →	-0.285	-3.576	.007	.002	3	3
COAD	GABRE →	-0.741	-3.449	.005	.005	2	4
UCEC	PDHX →	+0.373	+1.649	<.001	<.001	3	3
UCEC	NUP98 →	+0.236	+1.254	.008	.006	3	3
UCEC	KCNK15 →	-0.911	-1.338	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,573 associations by consensus.

MIR6803 by ARHGAP36 expression — COAD

Explore this box plot interactively →