Across TCGA patient cohorts, ARHGAP30 mutation is significantly associated with the RNA expression of many other genes, with 6,286 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARHGAP30-associated genes across cancer lineages are SPC24, ZNF232, and TSEN34. Each is linked with ARHGAP30 in more than 3 cancer types. Because this analysis shows association rather than direction, both ARHGAP30-to-partner and partner-to-ARHGAP30 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP30→partner) and Y-score (partner→ARHGAP30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SPC24 →	+0.438	+2.700	.009	.005	3	4
COAD	ZNF232 →	+0.730	+3.584	<.001	.002	3	4
UCEC	TSEN34 →	+0.315	+1.632	.002	.005	3	4
UCEC	ORC1 →	+0.965	+1.830	<.001	<.001	3	4
UCEC	SRRT →	+0.362	+3.392	<.001	<.001	3	4
UCEC	KHSRP →	+0.628	+2.312	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,286 associations by consensus.

Exploration

ARHGAP30 survival (RNA) · tumor vs normal (RNA) · all ARHGAP30 data types