ARHGAP29

Across TCGA patient cohorts, ARHGAP29 mutation is significantly associated with the RNA expression of many other genes, with 5,218 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARHGAP29-associated genes across cancer lineages are MIR6894, ZFYVE19, and ORC6. Each is linked with ARHGAP29 in more than 3 cancer types. Because this analysis shows association rather than direction, both ARHGAP29-to-partner and partner-to-ARHGAP29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6894 grouped by ARHGAP29-low versus ARHGAP29-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP29→partner) and Y-score (partner→ARHGAP29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR6894 →	+0.237	+3.284	<.001	.006	3	4
UCEC	ZFYVE19 →	+0.365	+1.765	<.001	<.001	3	4
UCEC	ORC6 →	+0.799	+2.283	<.001	<.001	3	4
UCEC	TAF9 →	+0.773	+2.584	<.001	<.001	3	3
UCEC	LIN7C →	+0.413	+1.724	.004	.002	3	3
UCEC	SUV39H2 →	+0.489	+1.679	.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,218 associations by consensus.

MIR6894 by ARHGAP29 expression — BRCA

Explore this box plot interactively →