ARHGAP29

Across TCGA pan-cancer cohorts, ARHGAP29 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of ARHGAP29’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where ARHGAP29 RNA is repressed in tumor relative to normal tissue. In most cancer types ARHGAP29 is over-expressed in tumor, although a few such as KICH and LUAD show the opposite, repressed pattern.

KICH, LUAD, and LUSC are the cancer types where ARHGAP29 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ARHGAP29 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	III,IV	−3.047	<.001	11	view →
LUAD	Female	III,IV	−1.622	<.001	9	view →
LUSC	Female	All	−2.639	<.001	8	view →
THCA	All	II,III,IV	−0.569	.007	5	view →
HNSC	Female	III,IV	+1.301	.001	4	view →
BRCA	Female	All	−0.551	<.001	4	view →
CHOL	All	All	+1.751	<.001	3	view →
KIRC	Male	III,IV	−0.428	.030	3	view →
UCEC	All	All	−1.147	<.001	2	view →
KIRP	All	II,III,IV	+0.864	.023	2	view →
PRAD	All	All	+0.360	.014	2	view →
BLCA	Female	IV	+1.573	.037	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

ARHGAP29–KICH

Open the KICH breakdown →