ARHGAP29

Across TCGA cell cohorts, ARHGAP29 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,105 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ARHGAP29-associated GO terms across cancer lineages are Regulation of actin filament organization, Regulation of cellular component size, and Regulation of cell-matrix adhesion. Each is linked with ARHGAP29 in more than 13 cancer types. Because this analysis shows association rather than direction, both ARHGAP29-to-partner and partner-to-ARHGAP29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of actin filament organization grouped by ARHGAP29-low versus ARHGAP29-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP29→partner) and Y-score (partner→ARHGAP29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of actin filament organization →	+0.065	+2.914	.007	.005	3	14
BREAST	Regulation of cellular component size →	+0.031	+1.219	.001	.002	3	13
BONE	Regulation of cell-matrix adhesion →	+0.135	+2.724	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Positive regulation of focal adhesion assembly →	+0.199	+3.440	.002	<.001	3	12
BONE	Integrin-mediated signaling pathway →	+0.229	+3.104	<.001	<.001	3	12
LUNG_NSCLC_LUAD	Rho protein signal transduction →	+0.103	+1.699	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,105 associations by consensus.

Regulation of actin filament organization by ARHGAP29 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →