ARHGAP29

Across TCGA cell cohorts, ARHGAP29 mutation is significantly associated with the RNA expression of many other genes, with 673 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARHGAP29-associated genes across cancer lineages are SCOC, PPP1CC, and KATNA1. Each is linked with ARHGAP29 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGAP29-to-partner and partner-to-ARHGAP29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCOC grouped by ARHGAP29-low versus ARHGAP29-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP29→partner) and Y-score (partner→ARHGAP29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SCOC →	+0.729	+3.169	.009	.009	3	2
LARGE_INTESTINE	PPP1CC →	+0.371	+3.321	.005	.003	3	2
LARGE_INTESTINE	KATNA1 →	+0.487	+3.321	.001	.003	3	2
PANCREAS	OR10V1 →	+0.036	+5.000	<.001	.006	3	1
PANCREAS	DAZ3 →	+0.929	+5.000	<.001	.006	3	1
BLOOD_Myeloma	POTEB2 →	+0.702	+4.754	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 673 associations by consensus.

SCOC by ARHGAP29 expression — LARGE_INTESTINE

Explore this box plot interactively →