ARHGAP27P1-BPTFP1-KPNA2P3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ARHGAP27P1-BPTFP1-KPNA2P3 mutation is significantly associated with the RNA expression of many other genes, with 176 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARHGAP27P1-BPTFP1-KPNA2P3-associated genes across cancer lineages are MRPL32P1, RNU6-502P, and TRAJ34. Each is linked with ARHGAP27P1-BPTFP1-KPNA2P3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGAP27P1-BPTFP1-KPNA2P3-to-partner and partner-to-ARHGAP27P1-BPTFP1-KPNA2P3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP27P1-BPTFP1-KPNA2P3→partner) and Y-score (partner→ARHGAP27P1-BPTFP1-KPNA2P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCMRPL32P1 →+0.171+6.569<.001.00132
LUADRNU6-502P →+0.266+5.631.002.00432
UCECTRAJ34 →+0.698+2.475.001.00932
LUSCPOLR2LP1 →+0.297+4.312<.001.00732
LUSCHMGN1P20 →+0.250+4.287<.001.00832
HNSCRNU6-492P →+0.478+7.954<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 176 associations by consensus.

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