ARHGAP27P1-BPTFP1-KPNA2P3

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ARHGAP27P1-BPTFP1-KPNA2P3 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ARHGAP27P1-BPTFP1-KPNA2P3 data layer compared with 4 for mutation status.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher ARHGAP27P1-BPTFP1-KPNA2P3 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ARHGAP27P1-BPTFP1-KPNA2P3 expression acts as an unfavorable survival marker, although some lineages such as BLCA and SKCM show a favorable association.

BLCA, KIRC, and SKCM are the cancer types where ARHGAP27P1-BPTFP1-KPNA2P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCAOSTertileAll0.7950.633<.00175view →
KIRCDFSTertileAll0.4960.741<.00168view →
SKCMOSMedianAll0.3950.244<.00154view →
COADDFSTertileAll0.4550.748<.00139view →
PAADOSQuartileII,III,IV0.5710.252.00735view →
PRADDFSMedianAll0.8370.926.00126view →
ACCDFSTertileIII,IV0.0790.646<.00123view →
LGGDFSTertileAll0.7880.886<.00118view →
READOSMedianIII,IV0.7431.000.01416view →
UVMDFSTertileIII,IV0.2720.851.00515view →
LIHCDFSQuartileAll0.3380.494.00712view →
STADDFSQuartileIII,IV0.3660.599.01210view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

Exploration