ARHGAP27P1-BPTFP1-KPNA2P3

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ARHGAP27P1-BPTFP1-KPNA2P3 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARHGAP27P1-BPTFP1-KPNA2P3-associated genes across cancer lineages are pDC, mv Endothelial cells, and Endothelial cells. Each is linked with ARHGAP27P1-BPTFP1-KPNA2P3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGAP27P1-BPTFP1-KPNA2P3-to-partner and partner-to-ARHGAP27P1-BPTFP1-KPNA2P3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP27P1-BPTFP1-KPNA2P3→partner) and Y-score (partner→ARHGAP27P1-BPTFP1-KPNA2P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECpDC →+0.067+2.839.012.03431
UCECmv Endothelial cells →-0.037-3.159.004.02012
UCECEndothelial cells →-0.046-3.127.026.02011
UCEClymphatic Endothelial cells →-0.030-3.116.022.02011
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration