ARHGAP27

Across TCGA patient cohorts, ARHGAP27 protein abundance is significantly associated with the RNA expression of many other genes, with 15,403 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ARHGAP27-associated genes across cancer lineages are DAPP1, ANKRD22, and TLCD5. Each is linked with ARHGAP27 in more than 6 cancer types. Because this analysis shows association rather than direction, both ARHGAP27-to-partner and partner-to-ARHGAP27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP27 versus DAPP1 in BRCA, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP27→partner) and Y-score (partner→ARHGAP27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DAPP1 →	+1.062	+0.354	<.001	<.001	3	7
HNSC	ANKRD22 →	+1.037	+0.243	<.001	<.001	2	7
HNSC	TLCD5 →	-0.711	-0.262	<.001	<.001	3	6
BRCA	SLC25A14 →	-0.442	-0.279	.003	<.001	3	5
BRCA	PCNX4 →	-0.527	-0.307	.001	<.001	3	5
BRCA	DYNC2H1 →	-0.565	-0.201	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,403 associations by consensus.

ARHGAP27 vs DAPP1 — BRCA

Explore this scatter interactively →