ARHGAP25

Across TCGA cell cohorts, ARHGAP25 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,015 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARHGAP25-associated GO terms across cancer lineages are Negative regulation of protein catabolic process, Positive regulation of matrix metallopeptidase secretion, and Negative regulation of myoblast fusion. Each is linked with ARHGAP25 in more than 8 cancer types. Because this analysis shows association rather than direction, both ARHGAP25-to-partner and partner-to-ARHGAP25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein catabolic process grouped by ARHGAP25-low versus ARHGAP25-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP25→partner) and Y-score (partner→ARHGAP25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of protein catabolic process →	+0.066	+0.836	.002	.001	3	9
SOFT_TISSUE	Positive regulation of matrix metallopeptidase secretion →	-0.153	-1.037	<.001	<.001	3	8
OVARY	Negative regulation of myoblast fusion →	+0.085	+0.581	<.001	.001	3	8
STOMACH	Regulation of DNA-templated transcription elongation →	+0.070	+0.762	<.001	<.001	2	9
SOFT_TISSUE	Regulation of mRNA processing →	+0.052	+0.943	.003	<.001	3	7
OVARY	Intrinsic apoptotic signaling pathway →	+0.046	+0.877	.002	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,015 associations by consensus.

Negative regulation of protein catabolic process by ARHGAP25 expression — OVARY

Explore this box plot interactively →