ARHGAP24

Across TCGA patient cohorts, ARHGAP24 mutation is significantly associated with the RNA expression of many other genes, with 5,744 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARHGAP24-associated genes across cancer lineages are CCDC153, BACH1-IT3, and TMEM269. Each is linked with ARHGAP24 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARHGAP24-to-partner and partner-to-ARHGAP24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC153 grouped by ARHGAP24-low versus ARHGAP24-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP24→partner) and Y-score (partner→ARHGAP24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCDC153 →	-0.791	-1.954	<.001	<.001	3	3
KIRP	BACH1-IT3 →	+0.127	+4.230	.001	.008	3	3
UCEC	TMEM269 →	+0.169	+1.769	<.001	<.001	3	2
UCEC	RNA5SP411 →	+0.773	+1.393	<.001	.005	3	2
UCEC	RNA5SP412 →	+0.342	+1.619	.001	.002	3	2
UCEC	SRCIN1 →	-0.680	-2.126	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,744 associations by consensus.

CCDC153 by ARHGAP24 expression — UCEC

Explore this box plot interactively →