ARHGAP24

Across TCGA cell cohorts, ARHGAP24 mutation is significantly associated with the RNA expression of many other genes, with 457 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ARHGAP24-associated genes across cancer lineages are ZNF771, CCR8, and BHLHA9. Each is linked with ARHGAP24 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGAP24-to-partner and partner-to-ARHGAP24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF771 grouped by ARHGAP24-low versus ARHGAP24-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP24→partner) and Y-score (partner→ARHGAP24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ZNF771 →	+0.591	+3.064	.002	.009	3	2
SOFT_TISSUE	CCR8 →	+0.022	+5.369	<.001	.004	3	1
SOFT_TISSUE	BHLHA9 →	+0.036	+5.977	<.001	.001	3	1
SOFT_TISSUE	GOLGA6L6 →	+0.013	+5.369	<.001	.004	3	1
BLOOD_Myeloma	UNCX →	+0.006	+4.807	<.001	.006	3	1
LUNG_NSCLC_LUAD	CCR6 →	+0.077	+2.536	.003	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 457 associations by consensus.

ZNF771 by ARHGAP24 expression — LARGE_INTESTINE

Explore this box plot interactively →