ARHGAP21

Across TCGA cell cohorts, ARHGAP21 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,994 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ARHGAP21-associated GO terms across cancer lineages are Establishment of Golgi localization, Golgi localization, and Regulation of intracellular transport. Each is linked with ARHGAP21 in more than 17 cancer types. Because this analysis shows association rather than direction, both ARHGAP21-to-partner and partner-to-ARHGAP21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of Golgi localization grouped by ARHGAP21-low versus ARHGAP21-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP21→partner) and Y-score (partner→ARHGAP21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Establishment of Golgi localization →	+0.151	+0.979	<.001	<.001	3	18
BONE	Golgi localization →	+0.160	+1.297	<.001	<.001	3	17
OVARY	Regulation of intracellular transport →	+0.056	+0.824	<.001	.003	3	13
BONE	Positive regulation of plasma membrane repair →	+0.293	+0.698	<.001	.001	3	12
URINARY_TRACT	Negative regulation of cilium assembly →	+0.079	+0.926	<.001	<.001	3	12
LIVER	[2Fe-2S] cluster assembly →	-0.084	-0.839	.004	.003	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,994 associations by consensus.

Establishment of Golgi localization by ARHGAP21 expression — BONE

Explore this box plot interactively →