ARHGAP18

Across TCGA patient cohorts, ARHGAP18 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,814 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARHGAP18-associated proteins across cancer lineages are AFG3L2, PPP1R18, and STAB1. Each is linked with ARHGAP18 in more than 6 cancer types. Because this analysis shows association rather than direction, both ARHGAP18-to-partner and partner-to-ARHGAP18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARHGAP18 versus AFG3L2 in OV, with a Pearson correlation of -0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP18→partner) and Y-score (partner→ARHGAP18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	AFG3L2 →	-0.557	-0.806	<.001	<.001	3	7
OV	PPP1R18 →	+0.489	+0.658	.001	<.001	3	7
GBM	STAB1 →	+0.570	+0.636	<.001	<.001	3	6
HNSC	EVL →	+0.636	+0.549	<.001	.007	3	6
GBM	FOLR2 →	+0.656	+0.448	<.001	<.001	3	6
LSCC	MRPS22 →	-0.371	-0.436	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,814 associations by consensus.

ARHGAP18 vs AFG3L2 — OV

Explore this scatter interactively →