Across TCGA patient cohorts, ARHGAP11A protein abundance is significantly associated with the RNA expression of many other genes, with 1,081 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ARHGAP11A-associated genes across cancer lineages are SLC6A1-AS1, GALNT15, and SSB. Each is linked with ARHGAP11A in more than 1 cancer types. Because this analysis shows association rather than direction, both ARHGAP11A-to-partner and partner-to-ARHGAP11A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARHGAP11A→partner) and Y-score (partner→ARHGAP11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SLC6A1-AS1 →	-0.589	-1.694	.002	<.001	3	2
BRCA	GALNT15 →	-1.851	-1.481	.003	<.001	3	2
LSCC	SSB →	+0.739	+0.713	<.001	.001	3	2
LSCC	IGFBP3 →	-1.859	-0.831	<.001	.003	3	2
LSCC	VEGFC →	-1.145	-0.741	<.001	<.001	3	2
BRCA	BMP1 →	-1.008	-0.910	.007	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,081 associations by consensus.

Exploration

ARHGAP11A survival (RNA) · tumor vs normal (RNA) · all ARHGAP11A data types