ARFRP1

Across TCGA patient cohorts, ARFRP1 mutation is significantly associated with the RNA expression of many other genes, with 287 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARFRP1-associated genes across cancer lineages are PABPC1L2B-AS1, MIR3162, and RNU6-165P. Each is linked with ARFRP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARFRP1-to-partner and partner-to-ARFRP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PABPC1L2B-AS1 grouped by ARFRP1-low versus ARFRP1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARFRP1→partner) and Y-score (partner→ARFRP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PABPC1L2B-AS1 →	+0.034	+7.816	<.001	.008	3	3
BLCA	MIR3162 →	+0.707	+4.840	<.001	.002	3	2
LUAD	RNU6-165P →	+0.352	+7.930	<.001	.008	3	2
BLCA	MIR4796 →	+0.300	+5.018	<.001	.004	3	1
BLCA	PMM2P1 →	+0.057	+5.289	<.001	.003	3	1
COAD	OR9Q2 →	+0.037	+5.136	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 287 associations by consensus.

PABPC1L2B-AS1 by ARFRP1 expression — SKCM

Explore this box plot interactively →