ARFIP2

Across TCGA patient cohorts, ARFIP2 mutation is significantly associated with the RNA expression of many other genes, with 1,649 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARFIP2-associated genes across cancer lineages are RPS26P43, RNU6-470P, and RNU6-622P. Each is linked with ARFIP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARFIP2-to-partner and partner-to-ARFIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPS26P43 grouped by ARFIP2-low versus ARFIP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARFIP2→partner) and Y-score (partner→ARFIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPS26P43 →	+0.253	+1.583	.002	.009	3	2
LUAD	RNU6-470P →	+0.153	+5.748	<.001	.001	3	2
UCEC	RNU6-622P →	+0.178	+2.524	.004	.006	3	2
UCEC	RNU6-1064P →	+0.596	+2.269	<.001	<.001	3	2
STAD	RN7SKP181 →	+0.346	+4.691	<.001	.003	3	2
UCEC	PPIAP17 →	+0.091	+2.356	.008	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,649 associations by consensus.

RPS26P43 by ARFIP2 expression — UCEC

Explore this box plot interactively →