ARFGEF3

Across TCGA patient cohorts, ARFGEF3 protein abundance is significantly associated with the RNA expression of many other genes, with 16,396 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ARFGEF3-associated genes across cancer lineages are HID1, PBOV1, and MAP7. Each is linked with ARFGEF3 in more than 7 cancer types. Because this analysis shows association rather than direction, both ARFGEF3-to-partner and partner-to-ARFGEF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARFGEF3 versus HID1 in BRCA, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARFGEF3→partner) and Y-score (partner→ARFGEF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HID1 →	+1.334	+0.628	<.001	<.001	3	8
LUAD	PBOV1 →	+1.000	+0.598	<.001	<.001	3	8
GBM	MAP7 →	+1.018	+0.463	<.001	<.001	3	7
BRCA	C9orf152 →	+1.742	+0.591	<.001	<.001	3	7
BRCA	SLC44A4 →	+2.319	+0.540	<.001	<.001	3	7
HNSC	ILDR1 →	+0.930	+0.592	.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,396 associations by consensus.

ARFGEF3 vs HID1 — BRCA

Explore this scatter interactively →