ARFGEF1

Across TCGA patient cohorts, ARFGEF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,151 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ARFGEF1-associated proteins across cancer lineages are NCOA2, YTHDF3, and VCPIP1. Each is linked with ARFGEF1 in more than 8 cancer types. Because this analysis shows association rather than direction, both ARFGEF1-to-partner and partner-to-ARFGEF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARFGEF1 versus NCOA2 in BRCA, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ARFGEF1→partner) and Y-score (partner→ARFGEF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NCOA2 →	+0.409	+0.875	<.001	<.001	3	8
OV	YTHDF3 →	+0.273	+0.697	.003	.003	2	9
OV	VCPIP1 →	+0.334	+0.883	<.001	<.001	3	8
BRCA	ARFGEF1_S1555 →	+0.593	+0.713	<.001	<.001	3	6
BRCA	TCEA1 →	+0.396	+0.981	<.001	<.001	3	6
LUAD	STAU2 →	+0.337	+0.613	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,151 associations by consensus.

ARFGEF1 vs NCOA2 — BRCA

Explore this scatter interactively →