ARF5

Across TCGA patient cohorts, ARF5 mutation is significantly associated with the RNA expression of many other genes, with 742 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ARF5-associated genes across cancer lineages are RNU4-15P, TAAR5, and RNA5SP377. Each is linked with ARF5 in more than 2 cancer types. Because this analysis shows association rather than direction, both ARF5-to-partner and partner-to-ARF5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-15P grouped by ARF5-low versus ARF5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARF5→partner) and Y-score (partner→ARF5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU4-15P →	+0.198	+2.840	.003	.004	3	3
UCEC	TAAR5 →	+0.170	+2.055	.002	.006	3	2
LUSC	RNA5SP377 →	+0.153	+4.780	<.001	.003	3	2
LUAD	MTCO3P17 →	+0.173	+5.076	<.001	.001	3	2
LUSC	RPS27P20 →	+0.323	+3.427	<.001	.003	3	2
LUSC	CRYAA2 →	+0.121	+3.142	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 742 associations by consensus.

RNU4-15P by ARF5 expression — UCEC

Explore this box plot interactively →