ARF3

Across TCGA patient cohorts, ARF3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,238 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ARF3-associated genes across cancer lineages are SMCHD1, KLF3, and RAB38. Each is linked with ARF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARF3-to-partner and partner-to-ARF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARF3 versus SMCHD1 in LUAD, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARF3→partner) and Y-score (partner→ARF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SMCHD1 →	-0.470	-0.364	.008	.006	3	2
HNSC	KLF3 →	-0.886	-1.019	.009	.006	3	2
HNSC	RAB38 →	-1.660	-1.423	.008	.001	3	2
LUAD	NAB1 →	-0.492	-0.419	.002	.002	3	2
HNSC	DENND2C →	-0.750	-1.182	.001	<.001	3	2
LUAD	NEMP2 →	-0.409	-0.294	.004	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,238 associations by consensus.

ARF3 vs SMCHD1 — LUAD

Explore this scatter interactively →