AREL1

Across TCGA patient cohorts, AREL1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,016 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible AREL1-associated genes across cancer lineages are SH2B3, ERRFI1, and ACTRT1. Each is linked with AREL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AREL1-to-partner and partner-to-AREL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AREL1 versus SH2B3 in UCEC, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AREL1→partner) and Y-score (partner→AREL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SH2B3 →	+0.611	+1.868	.004	.006	3	1
UCEC	ERRFI1 →	-1.256	-1.750	.005	.007	3	1
UCEC	ACTRT1 →	+0.401	+2.173	<.001	<.001	3	1
UCEC	AANAT →	+0.695	+1.455	<.001	.004	3	1
UCEC	GJA9 →	+0.233	+1.455	.001	.004	3	1
UCEC	MYBPC3 →	+0.324	+1.521	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,016 associations by consensus.

AREL1 vs SH2B3 — UCEC

Explore this scatter interactively →