Across TCGA patient cohorts, ARAFP3 RNA expression is significantly associated with the mutation status of many other genes, with 102 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible ARAFP3-associated genes across cancer lineages are XPO6, ADAM8, and TRIP11. Each is linked with ARAFP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ARAFP3-to-partner and partner-to-ARAFP3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARAFP3→partner) and Y-score (partner→ARAFP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	XPO6 →	+5.119	+0.042	.002	<.001	3	2
BRCA	ADAM8 →	+7.731	+0.064	.009	<.001	3	2
OV	TRIP11 →	+4.704	+0.025	.004	<.001	3	1
OV	EGF →	+5.704	+0.068	.001	<.001	3	1
OV	COL27A1 →	+5.704	+0.066	.001	<.001	3	1
ESCA	CRNKL1 →	+5.450	+0.069	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 102 associations by consensus.

Exploration

ARAFP3 survival (RNA) · tumor vs normal (RNA) · all ARAFP3 data types