ARAF

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ARAF RNA expression is significantly associated with the go_rna of many other GO terms, with 3,267 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ARAF-associated GO terms across cancer lineages are Growth hormone secretion, Type 2 mitophagy, and Tubulin deacetylation. Each is linked with ARAF in more than 17 cancer types. Because this analysis shows association rather than direction, both ARAF-to-partner and partner-to-ARAF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Growth hormone secretion grouped by ARAF-low versus ARAF-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ARAF→partner) and Y-score (partner→ARAF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHGrowth hormone secretion →+0.116+0.629<.001<.001318
URINARY_TRACTType 2 mitophagy →+0.203+1.093<.001<.001313
SKINTubulin deacetylation →+0.160+0.721<.001<.001312
BREASTPost-Golgi vesicle-mediated transport →+0.089+1.000<.001<.001312
SKINPositive regulation of type 2 mitophagy →+0.151+0.664<.001<.001311
SKINPositive regulation of intracellular steroid hormone receptor signaling pathway →+0.141+0.654<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,267 associations by consensus.

Growth hormone secretion by ARAF expression — STOMACH

Box plot of Growth hormone secretion in ARAF-low vs ARAF-high samples in STOMACH.

Explore this box plot interactively →

Exploration