ARAF

Across TCGA cell cohorts, ARAF protein abundance is significantly associated with the RNA expression of many other genes, with 1,348 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ARAF-associated genes across cancer lineages are TUBD1, CYB5D1, and CHMP4B. Each is linked with ARAF in more than 3 cancer types. Because this analysis shows association rather than direction, both ARAF-to-partner and partner-to-ARAF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ARAF versus TUBD1 in OESOPHAGUS, with a Pearson correlation of -0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ARAF→partner) and Y-score (partner→ARAF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	TUBD1 →	-1.253	-2.901	.002	.001	3	4
BLOOD_Lymphoma	CYB5D1 →	-1.205	-1.492	.008	.007	3	3
BLOOD_Leukemia	CHMP4B →	+0.724	+1.762	.001	.002	3	3
BLOOD_Leukemia	MOB1A →	+1.098	+2.000	<.001	<.001	3	3
BLOOD_Leukemia	MUTYH →	+0.884	+1.851	.004	.004	3	3
BLOOD_Leukemia	HCN3 →	+1.053	+1.692	.004	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,348 associations by consensus.

ARAF vs TUBD1 — OESOPHAGUS

Explore this scatter interactively →