AQR

Across TCGA patient cohorts, AQR protein abundance is significantly associated with the protein abundance of many other proteins, with 33,811 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AQR-associated proteins across cancer lineages are SF3B1, SIN3A, and SNRNP200. Each is linked with AQR in more than 9 cancer types. Because this analysis shows association rather than direction, both AQR-to-partner and partner-to-AQR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AQR versus SF3B1 in GBM, with a Pearson correlation of 0.86.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AQR→partner) and Y-score (partner→AQR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SF3B1 →	+0.324	+0.327	<.001	<.001	3	10
GBM	SIN3A →	+0.380	+0.312	<.001	<.001	3	10
GBM	SNRNP200 →	+0.335	+0.329	<.001	<.001	3	10
HNSC	TRRAP →	+0.286	+0.242	<.001	<.001	3	10
GBM	CDC73 →	+0.368	+0.316	<.001	<.001	3	10
GBM	DIDO1 →	+0.336	+0.319	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 33,811 associations by consensus.

AQR vs SF3B1 — GBM

Explore this scatter interactively →