AQP7P4

Across TCGA patient cohorts, AQP7P4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,142 significant associations in total. STAD shows the largest number of these associations.

The most reproducible AQP7P4-associated GO terms across cancer lineages are Regulation of lipid biosynthetic process, Positive regulation of cellular response to insulin stimulus, and Neuron projection extension involved in neuron projection guidance. Each is linked with AQP7P4 in more than 5 cancer types. Because this analysis shows association rather than direction, both AQP7P4-to-partner and partner-to-AQP7P4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of lipid biosynthetic process grouped by AQP7P4-low versus AQP7P4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AQP7P4→partner) and Y-score (partner→AQP7P4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of lipid biosynthetic process →	+0.029	+0.023	<.001	<.001	3	6
STAD	Positive regulation of cellular response to insulin stimulus →	+0.039	+0.018	<.001	<.001	3	5
STAD	Neuron projection extension involved in neuron projection guidance →	+0.036	+0.020	<.001	<.001	3	5
STAD	Regulation of insulin receptor signaling pathway →	+0.046	+0.020	<.001	<.001	3	5
SKCM	Axon guidance →	+0.024	+0.015	<.001	<.001	3	5
STAD	Actomyosin structure organization →	+0.040	+0.019	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,142 associations by consensus.

Regulation of lipid biosynthetic process by AQP7P4 expression — STAD

Explore this box plot interactively →