AQP7P4

Across TCGA pan-cancer cohorts, AQP7P4 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated AQP7P4 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher AQP7P4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated AQP7P4 expression acts as an unfavorable survival marker, although some lineages such as KIRP show a favorable association.

STAD, OV, and UCS are the cancer types where AQP7P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Tertile	All	0.203	0.439	.006	39	view →
OV	OS	Tertile	All	0.725	0.849	.010	18	view →
UCS	DFS	Tertile	All	0.126	0.523	.009	18	view →
LUAD	OS	Tertile	II,III,IV	0.336	0.753	.011	18	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
KIRP	DFS	Tertile	III,IV	0.830	0.528	.030	6	view →
LIHC	DFS	Quartile	II,III,IV	0.189	0.355	.031	5	view →
DLBC	OS	Tertile	All	0.613	0.945	.049	3	view →
ACC	OS	Tertile	All	0.555	0.831	.036	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

AQP7P4–STAD (DFS)

Open the STAD breakdown →