Across TCGA cell cohorts, AQP12A RNA expression is significantly associated with the go_rna of many other GO terms, with 252 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible AQP12A-associated GO terms across cancer lineages are Pyroptotic cell death, Adenylate cyclase-activating G protein-coupled receptor signaling pathway, and Negative regulation of protein deubiquitination. Each is linked with AQP12A in more than 2 cancer types. Because this analysis shows association rather than direction, both AQP12A-to-partner and partner-to-AQP12A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AQP12A→partner) and Y-score (partner→AQP12A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Pyroptotic cell death →	+0.190	+0.040	<.001	.006	3	3
PANCREAS	Adenylate cyclase-activating G protein-coupled receptor signaling pathway →	-0.058	-0.078	<.001	.001	3	3
PANCREAS	Negative regulation of protein deubiquitination →	+0.083	+0.054	.005	.008	3	3
OESOPHAGUS	Regulation of macrophage activation →	+0.065	+0.022	.002	.009	3	2
OESOPHAGUS	Negative regulation of catalytic activity →	+0.071	+0.032	<.001	.005	3	2
OESOPHAGUS	Negative regulation of innate immune response →	+0.076	+0.032	.007	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 252 associations by consensus.

Exploration

AQP12A survival (RNA) · tumor vs normal (RNA) · all AQP12A data types