AQP10

Across TCGA cell cohorts, AQP10 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,464 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AQP10-associated GO terms across cancer lineages are Regulation of Golgi to plasma membrane protein transport, Negative regulation of platelet-derived growth factor receptor signaling pathway, and Regulation of cell fate commitment. Each is linked with AQP10 in more than 3 cancer types. Because this analysis shows association rather than direction, both AQP10-to-partner and partner-to-AQP10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of Golgi to plasma membrane protein transport grouped by AQP10-low versus AQP10-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AQP10→partner) and Y-score (partner→AQP10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of Golgi to plasma membrane protein transport →	+0.105	+0.289	<.001	.007	3	3
BLOOD_Leukemia	Negative regulation of platelet-derived growth factor receptor signaling pathway →	+0.169	+1.091	<.001	<.001	3	3
BLOOD_Leukemia	Regulation of cell fate commitment →	+0.088	+0.554	<.001	.006	3	3
BLOOD_Leukemia	Mitochondrial gene expression →	+0.043	+0.771	<.001	.004	3	3
BLOOD_Leukemia	Cell-substrate junction organization →	+0.047	+0.658	<.001	.004	3	3
BLOOD_Leukemia	Positive regulation of ferroptosis →	+0.101	+0.655	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,464 associations by consensus.

Regulation of Golgi to plasma membrane protein transport by AQP10 expression — OESOPHAGUS

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