Across TCGA patient cohorts, APTR RNA expression is significantly associated with the protein abundance of many other proteins, with 15,168 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible APTR-associated proteins across cancer lineages are MDH2, MEPCE, and GTF2I. Each is linked with APTR in more than 5 cancer types. Because this analysis shows association rather than direction, both APTR-to-partner and partner-to-APTR results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (APTR→partner) and Y-score (partner→APTR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MDH2 →	+0.590	+0.712	<.001	<.001	3	6
GBM	MEPCE →	+0.330	+0.403	<.001	<.001	3	6
HNSC	GTF2I →	+0.428	+0.587	<.001	.001	3	6
LSCC	ZKSCAN1 →	+0.347	+0.611	<.001	<.001	3	5
HNSC	ZNF219_S114 →	+0.744	+0.882	<.001	<.001	3	5
GBM	HSP90B1_S447 →	-0.702	-0.636	.008	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,168 associations by consensus.

Exploration

APTR survival (RNA) · tumor vs normal (RNA) · all APTR data types