APP-DT

Across TCGA patient cohorts, APP-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 7,611 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible APP-DT-associated proteins across cancer lineages are APP, NEPRO, and SUCO_S1073. Each is linked with APP-DT in more than 4 cancer types. Because this analysis shows association rather than direction, both APP-DT-to-partner and partner-to-APP-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APP-DT versus APP in LSCC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (APP-DT→partner) and Y-score (partner→APP-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	APP →	+0.582	+0.162	<.001	<.001	3	5
OV	NEPRO →	-0.320	-0.397	.001	.002	3	4
LSCC	SUCO_S1073 →	+0.938	+0.233	<.001	.001	3	3
GBM	DCAF7 →	+0.170	+0.485	.004	.002	3	3
LSCC	GTF3C4 →	+0.342	+0.159	<.001	.001	3	3
OV	HLCS →	+0.364	+0.449	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,611 associations by consensus.

APP-DT vs APP — LSCC

Explore this scatter interactively →