APOOP1

Across TCGA patient cohorts, APOOP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,680 significant associations in total. STAD shows the largest number of these associations.

The most reproducible APOOP1-associated GO terms across cancer lineages are Reactive oxygen species metabolic process, Oxidative phosphorylation, and Lymphocyte activation involved in immune response. Each is linked with APOOP1 in more than 10 cancer types. Because this analysis shows association rather than direction, both APOOP1-to-partner and partner-to-APOOP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Reactive oxygen species metabolic process grouped by APOOP1-low versus APOOP1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (APOOP1→partner) and Y-score (partner→APOOP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Reactive oxygen species metabolic process →	+0.072	+0.075	<.001	<.001	3	11
STAD	Oxidative phosphorylation →	+0.098	+0.074	<.001	<.001	3	11
STAD	Lymphocyte activation involved in immune response →	+0.073	+0.081	<.001	<.001	3	11
STAD	Pyruvate metabolic process →	+0.074	+0.074	<.001	<.001	3	10
STAD	Canonical NF-kappaB signal transduction →	+0.082	+0.072	<.001	<.001	3	10
STAD	Positive regulation of NF-kappaB transcription factor activity →	+0.067	+0.075	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,680 associations by consensus.

Reactive oxygen species metabolic process by APOOP1 expression — STAD

Explore this box plot interactively →