Across TCGA patient cohorts, APOM mutation is significantly associated with the RNA expression of many other genes, with 906 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible APOM-associated genes across cancer lineages are MIR4510, LINC02348, and WHAMMP3. Each is linked with APOM in more than 1 cancer types. Because this analysis shows association rather than direction, both APOM-to-partner and partner-to-APOM results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APOM→partner) and Y-score (partner→APOM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4510 →	+0.208	+3.716	<.001	.002	3	2
UCEC	LINC02348 →	+0.444	+2.456	<.001	.003	3	1
UCEC	WHAMMP3 →	+0.242	+2.566	<.001	.009	3	1
SKCM	GTF3AP2 →	+0.158	+5.037	<.001	.009	3	1
SKCM	DNM1P28 →	+0.107	+5.224	<.001	.007	3	1
SKCM	LINC02186 →	+0.051	+5.362	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 906 associations by consensus.

Exploration

APOM survival (RNA) · tumor vs normal (RNA) · all APOM data types