APOL5

mutation — cross-omics
Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, APOL5 mutation is significantly associated with the drug of many other genes, with 1 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible APOL5-associated genes across cancer lineages are CCT245232. Each is linked with APOL5 in more than 1 cancer types. Because this analysis shows association rather than direction, both APOL5-to-partner and partner-to-APOL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCT245232 grouped by APOL5-low versus APOL5-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APOL5→partner) and Y-score (partner→APOL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINCCT245232 →+0.325+2.742.018.04311
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

CCT245232 by APOL5 expression — SKIN

Box plot of CCT245232 in APOL5-low vs APOL5-high samples in SKIN.

Explore this box plot interactively →

Exploration