Across TCGA patient cohorts, APOBR protein abundance is significantly associated with the RNA expression of many other genes, with 18,515 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible APOBR-associated genes across cancer lineages are RASGRP4, NCF4, and HCK. Each is linked with APOBR in more than 9 cancer types. Because this analysis shows association rather than direction, both APOBR-to-partner and partner-to-APOBR results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APOBR→partner) and Y-score (partner→APOBR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RASGRP4 →	+0.514	+0.615	<.001	<.001	3	10
GBM	NCF4 →	+1.148	+0.644	<.001	<.001	3	9
GBM	HCK →	+1.063	+0.622	<.001	<.001	3	9
OV	IL4I1 →	+1.507	+0.470	<.001	.001	3	9
OV	LILRB1 →	+0.906	+0.491	<.001	<.001	3	9
OV	DOCK8 →	+1.122	+0.578	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,515 associations by consensus.

Exploration

APOBR survival (RNA) · tumor vs normal (RNA) · all APOBR data types