Across TCGA pan-cancer cohorts, APOBR RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of APOBR’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where APOBR RNA is more highly expressed in tumor relative to normal tissue. In most cancer types APOBR is over-expressed in tumor, although a few such as COAD and LUAD show the opposite, repressed pattern.
KIRC, COAD, and KIRP are the cancer types where APOBR tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in APOBR RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.