APOBEC3C

Across TCGA patient cohorts, APOBEC3C RNA expression is significantly associated with the protein abundance of many other proteins, with 16,858 significant associations in total. GBM shows the largest number of these associations.

The most reproducible APOBEC3C-associated proteins across cancer lineages are TRIM22, GBP2, and SERPINB9. Each is linked with APOBEC3C in more than 6 cancer types. Because this analysis shows association rather than direction, both APOBEC3C-to-partner and partner-to-APOBEC3C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APOBEC3C versus TRIM22 in OV, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (APOBEC3C→partner) and Y-score (partner→APOBEC3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TRIM22 →	+0.386	+0.659	<.001	<.001	3	7
GBM	GBP2 →	+0.739	+0.861	<.001	<.001	3	7
OV	SERPINB9 →	+0.512	+0.848	<.001	<.001	3	7
OV	APOBEC3G →	+0.561	+0.729	<.001	<.001	3	7
BRCA	MYO1G →	+0.445	+0.815	<.001	<.001	3	6
BRCA	RAC2 →	+0.742	+0.993	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,858 associations by consensus.

APOBEC3C vs TRIM22 — OV

Explore this scatter interactively →