APOBEC3B-AS1

Across TCGA patient cohorts, APOBEC3B-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,785 significant associations in total. STAD shows the largest number of these associations.

The most reproducible APOBEC3B-AS1-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Response to UV, and DNA dealkylation. Each is linked with APOBEC3B-AS1 in more than 13 cancer types. Because this analysis shows association rather than direction, both APOBEC3B-AS1-to-partner and partner-to-APOBEC3B-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA metabolic process grouped by APOBEC3B-AS1-low versus APOBEC3B-AS1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (APOBEC3B-AS1→partner) and Y-score (partner→APOBEC3B-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA metabolic process →	+0.055	+0.079	<.001	<.001	3	14
ESCA	Response to UV →	+0.058	+0.117	<.001	.002	3	13
DLBC	DNA dealkylation →	+0.074	+0.115	<.001	.001	3	13
ESCA	DNA synthesis involved in DNA repair →	+0.062	+0.152	<.001	<.001	3	13
DLBC	Endosomal transport →	+0.061	+0.228	.001	<.001	3	12
ESCA	Regulation of protein ubiquitination →	+0.067	+0.144	<.001	<.001	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,785 associations by consensus.

Positive regulation of DNA metabolic process by APOBEC3B-AS1 expression — STAD

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