APOA5

Across TCGA cell cohorts, APOA5 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible APOA5-associated genes across cancer lineages are LILRA1, C20orf85, and OR1L4. Each is linked with APOA5 in more than 1 cancer types. Because this analysis shows association rather than direction, both APOA5-to-partner and partner-to-APOA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LILRA1 grouped by APOA5-low versus APOA5-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APOA5→partner) and Y-score (partner→APOA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	LILRA1 →	+0.113	+4.930	<.001	.008	3	1
SOFT_TISSUE	C20orf85 →	+0.115	+5.369	<.001	.004	3	1
SOFT_TISSUE	OR1L4 →	+0.072	+5.369	<.001	.004	3	1
SOFT_TISSUE	C16orf78 →	+0.018	+5.369	.001	.004	3	1
SOFT_TISSUE	OR4D6 →	+0.046	+5.977	<.001	.001	3	1
SOFT_TISSUE	OR51L1 →	+0.036	+5.369	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

LILRA1 by APOA5 expression — SOFT_TISSUE

Explore this box plot interactively →