APLP1

Across TCGA patient cohorts, APLP1 RNA expression is significantly associated with the RNA expression of many other genes, with 14,656 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible APLP1-associated genes across cancer lineages are SPTBN4, TMEM151A, and KIRREL2. Each is linked with APLP1 in more than 28 cancer types. Because this analysis shows association rather than direction, both APLP1-to-partner and partner-to-APLP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APLP1 versus SPTBN4 in SCLC, with a Pearson correlation of 0.51.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APLP1→partner) and Y-score (partner→APLP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	SPTBN4 →	+1.998	+2.328	<.001	<.001	3	29
CHOL	TMEM151A →	+2.556	+2.175	<.001	<.001	3	29
UCS	KIRREL2 →	+2.608	+2.022	<.001	<.001	3	28
KICH	PRAF2 →	+1.148	+1.553	<.001	<.001	3	28
ACC	CAMK2N2 →	+1.655	+1.880	<.001	<.001	3	28
SCLC	MPP2 →	+1.296	+1.865	<.001	<.001	3	28

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,656 associations by consensus.

APLP1 vs SPTBN4 — SCLC

Explore this scatter interactively →