APH1B

Across TCGA patient cohorts, APH1B RNA expression is significantly associated with the protein abundance of many other proteins, with 19,228 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible APH1B-associated proteins across cancer lineages are YME1L1, MRPL1, and MRPS15. Each is linked with APH1B in more than 7 cancer types. Because this analysis shows association rather than direction, both APH1B-to-partner and partner-to-APH1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APH1B versus YME1L1 in BRCA, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (APH1B→partner) and Y-score (partner→APH1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	YME1L1 →	-0.380	-0.869	<.001	<.001	3	7
PDAC	MRPL1 →	-0.396	-0.304	<.001	.006	2	8
LSCC	MRPS15 →	-0.442	-0.510	<.001	<.001	3	7
LSCC	MRPS2 →	-0.453	-0.517	<.001	<.001	3	7
LSCC	MRPS35 →	-0.435	-0.533	<.001	<.001	3	7
PDAC	MRPS5 →	-0.395	-0.422	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,228 associations by consensus.

APH1B vs YME1L1 — BRCA

Explore this scatter interactively →