APH1B

Across TCGA patient cohorts, APH1B protein abundance is significantly associated with the RNA expression of many other genes, with 13,208 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible APH1B-associated genes across cancer lineages are ANKDD1A, MIR30E, and VN2R19P. Each is linked with APH1B in more than 1 cancer types. Because this analysis shows association rather than direction, both APH1B-to-partner and partner-to-APH1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APH1B versus ANKDD1A in LSCC, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APH1B→partner) and Y-score (partner→APH1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ANKDD1A →	+0.462	+0.252	.007	.005	3	2
LSCC	MIR30E →	+0.807	+0.390	.003	.004	3	2
GBM	VN2R19P →	+0.550	+0.281	.001	.001	3	2
LSCC	RASGRP2 →	+0.933	+0.524	.001	.001	3	2
LSCC	PTK6 →	-1.613	-0.334	.003	.004	3	1
LSCC	SLC52A3 →	-0.825	-0.298	.003	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,208 associations by consensus.

APH1B vs ANKDD1A — LSCC

Explore this scatter interactively →